Mediterranean Cruises

Explore the Mediterranean

Sail to multiple iconic destinations and only unpack once

Combine Cruise Line Offers With Our American Airlines Cruises Exclusives
  • You May Qualify for One or More Mediterranean Cruises Offers
Recommended Sailings

Mediterranean Cruises

  • Voyager of the Seas
    4.1 rating out of 5  (1,106 reviews)

    7 Night Italy & France

    Voyager of the Seas

    Departing from: Civitavecchia (Rome), Italy
    Ports of Call:
    • Naples, Italy
    • Messina, Sicily, Italy
    • La Spezia (Florence & Pisa), Italy
    • Cannes, France
    • Marseille (Provence), France
    • Barcelona, Spain
    Sailing Dates:
    • October 2025
    interior from
    $974
    $139pernight
    oceanview from
    $1,072
    $153pernight
    balcony from
    $1,413
    $202pernight
    suite from
    $4,450
    $636pernight
    Rewards & Bonus Offers:
    • AAdvantage® Members: Earn 2X Miles on Select Sailings
    • Exclusive Bonus: up to $100 to Spend Onboard
    • AAdvantage® Credit Cardmembers get even more miles
    • 60% Off Second Guest
    • Kids Sail Free!
    • 48-Hour Flash Sale: Up to $700 Instant Savings
     
    Interior from $974
    ($139pernight)
    4.1 rating out of 5  (1,106 reviews)
  • Allure of the Seas
    4.4 rating out of 5  (4,027 reviews)

    7 Night Western Mediterranean

    Allure of the Seas - Revitalized Ship!

    Departing from: Barcelona, Spain
    Ports of Call:
    • Palma De Mallorca, Balearic Islands
    • La Spezia (Florence & Pisa), Italy
    • Civitavecchia (Rome), Italy
    • Naples, Italy
    Sailing Dates:
    • May 2025
    • June 2025
    • July 2025
    • August 2025
    • September 2025
    • October 2025
    interior from
    $803
    $115pernight
    oceanview from
    $1,069
    $153pernight
    balcony from
    $1,273
    $182pernight
    suite from
    $2,265
    $324pernight
    Rewards & Bonus Offers:
    • AAdvantage® Members: Earn 2X Miles on Select Sailings
    • Exclusive Bonus: up to $100 to Spend Onboard
    • AAdvantage® Credit Cardmembers get even more miles
    • 60% Off Second Guest
    • Kids Sail Free!
    • 48-Hour Flash Sale: Up to $700 Instant Savings
     
    Interior from $803
    ($115pernight)
    4.4 rating out of 5  (4,027 reviews)
  • Sun Princess
    4.1 rating out of 5  (75 reviews)

    7 Night Mediterranean with France & Italy

    Sun Princess

    Departing from: Barcelona, Spain
    Ports of Call:
    • Gibraltar (U.K.)
    • Marseille (Provence), France
    • Genoa, Italy
    • La Spezia (Florence & Pisa), Italy
    • Civitavecchia (Rome), Italy
    Sailing Dates:
    • May 2025
    • August 2025
    • April 2026
    • May 2026
    • June 2026
    • July 2026
    • August 2026
    • September 2026
    • October 2026
    interior from
    $840
    $120pernight
    oceanview from
    $1,060
    $151pernight
    balcony from
    $1,310
    $187pernight
    suite from
    $1,739
    $248pernight
    Rewards & Bonus Offers:
    • AAdvantage® Members: Earn 2X Miles on Select Sailings
    • Exclusive: Free Onboard Savings Booklet - up to a $1,800 value!
    • AAdvantage® Credit Cardmembers get even more miles
    • Exclusive: Earn up to 20,000 bonus miles!
    • Drop & Go Sale: Limited Time Reduced Rates!
    • Spring Sale: Up to 50% Off, Free Upgrades & More
    • Call for rates too low to show!
     
    Interior from $840
    ($120pernight)
    4.1 rating out of 5  (75 reviews)
  • Celebrity Equinox
    4.3 rating out of 5  (1,963 reviews)

    9 Night Italian Riviera & France

    Celebrity Equinox

    Departing from: Civitavecchia (Rome), Italy
    Ports of Call:
    • Naples, Italy
    • La Spezia (Florence & Pisa), Italy
    • Portofino, Italy
    • Villefranche-Sur-Mer (Nice), France
    • Marseille (Provence), France
    • Barcelona, Spain
    Sailing Dates:
    • May 2025
    • July 2025
    • September 2025
    • October 2025
    interior from
    $1,057
    $117pernight
    oceanview from
    $1,158
    $129pernight
    balcony from
    $1,296
    $144pernight
    suite from
    $3,747
    $416pernight
    Rewards & Bonus Offers:
    • AAdvantage® Members: Earn 2X Miles on Select Sailings
    • CALL: up to a $75 FREE Dining Credit!
    • AAdvantage® Credit Cardmembers get even more miles
    • All-Included: Drinks & Wi-Fi
    • Spring Sale: 75% Off 2nd Guest + Up to $300 in Savings!
    • No Interest or Approval: Book with No Cruise Payment Due Today
     
    Was $4,146 – Save up to 75%
    Interior from $1,057
    ($117pernight)
    4.3 rating out of 5  (1,963 reviews)
  • Norwegian Epic
    3.7 rating out of 5  (3,127 reviews)

    10 Night Greek Isles: Santorini Athens & Florence

    Norwegian Epic - OPEN BAR!

    Departing from: Civitavecchia (Rome), Italy
    Ports of Call:
    • Santorini (Thira), Greece
    • Piraeus (Athens), Greece
    • Katakolon (Olympia), Greece
    • Valletta, Malta
    • Catania, Sicily, Italy
    • Naples (Pompeii), Italy
    • Livorno (Florence & Pisa), Italy
    • Cannes, France
    Sailing Dates:
    • May 2025
    interior from
    $1,032
    $103pernight
    oceanview from
    Call for availability
    balcony from
    $1,392
    $139pernight
    suite from
    $1,732
    $173pernight
    Rewards & Bonus Offers:
    • AAdvantage® Members: Earn 2X Miles on Select Sailings
    • Exclusive: Up to $300 to Spend on Board- Call
    • Limited-Time: Up to 25,000 AAdvantage® Bonus Miles
    • AAdvantage® Credit Cardmembers get even more miles
    • Kids Sail Free!
    • 50% Off All Cruises + Enhanced More at Sea Perks
     
    Interior from $1,032
    ($103pernight)
    3.7 rating out of 5  (3,127 reviews)
  • Norwegian Breakaway
    3.8 rating out of 5  (3,532 reviews)

    9 Night Mediterranean: Italy France & Spain

    Norwegian Breakaway - OPEN BAR!

    Departing from: Barcelona, Spain
    Ports of Call:
    • Cannes, France
    • Livorno (Florence & Pisa), Italy
    • Civitavecchia (Rome), Italy
    • Naples (Pompeii), Italy
    • Ibiza, Balearic Islands
    • Palma De Mallorca, Balearic Islands
    Sailing Dates:
    • May 2025
    interior from
    $950
    $106pernight
    oceanview from
    $1,120
    $124pernight
    balcony from
    $1,290
    $143pernight
    suite from
    Call for availability
    Rewards & Bonus Offers:
    • AAdvantage® Members: Earn 2X Miles on Select Sailings
    • Limited-Time: Up to 25,000 AAdvantage® Bonus Miles
    • AAdvantage® Credit Cardmembers get even more miles
    • Kids Sail Free!
    • 50% Off All Cruises + Enhanced More at Sea Perks
     
    Interior from $950
    ($106pernight)
    3.8 rating out of 5  (3,532 reviews)
  • Odyssey of the Seas
    4.5 rating out of 5  (490 reviews)

    7 Night Greek Isles

    Odyssey of the Seas

    Departing from: Civitavecchia (Rome), Italy
    Ports of Call:
    • Santorini (Thira), Greece
    • Kusadasi (Ephesus), Turkey
    • Mykonos, Greece
    • Naples, Italy
    Sailing Dates:
    • May 2025
    • June 2025
    • July 2025
    • August 2025
    • September 2025
    interior from
    $1,763
    $252pernight
    oceanview from
    $1,847
    $264pernight
    balcony from
    $2,123
    $303pernight
    suite from
    $3,059
    $437pernight
    Rewards & Bonus Offers:
    • AAdvantage® Members: Earn 2X Miles on Select Sailings
    • Exclusive Bonus: up to $100 to Spend Onboard
    • AAdvantage® Credit Cardmembers get even more miles
    • 60% Off Second Guest
    • Kids Sail Free!
    • 48-Hour Flash Sale: Up to $700 Instant Savings
     
    Was $2,756 – Save up to 36%
    Interior from $1,763
    ($252pernight)
    4.5 rating out of 5  (490 reviews)
  • Celebrity Infinity
    4.1 rating out of 5  (1,114 reviews)

    9 Night Best of Greece

    Celebrity Infinity

    Departing from: Piraeus (Athens), Greece
    Ports of Call:
    • Souda (Chania), Crete
    • Santorini (Thira), Greece
    • Kusadasi (Ephesus), Turkey
    • Mykonos, Greece
    • Kavala (Philippi), Greece
    • Thessaloniki, Greece
    Sailing Dates:
    • May 2025
    • August 2025
    • September 2025
    • October 2025
    interior from
    $984
    $109pernight
    oceanview from
    $1,154
    $128pernight
    balcony from
    $1,390
    $154pernight
    suite from
    $3,017
    $335pernight
    Rewards & Bonus Offers:
    • AAdvantage® Members: Earn 2X Miles on Select Sailings
    • CALL: up to a $75 FREE Dining Credit!
    • AAdvantage® Credit Cardmembers get even more miles
    • All-Included: Drinks & Wi-Fi
    • 3rd, 4th & 5th Guests Sail Free
    • Spring Sale: 75% Off 2nd Guest + Up to $300 in Savings!
     
    Was $4,228 – Save up to 77%
    Interior from $984
    ($109pernight)
    4.1 rating out of 5  (1,114 reviews)
  • Enchanted Princess
    4.4 rating out of 5  (320 reviews)

    7 Night Mediterranean & Aegean

    Enchanted Princess

    Departing from: Civitavecchia (Rome), Italy
    Ports of Call:
    • Naples (Pompeii), Italy
    • Santorini (Thira), Greece
    • Kusadasi (Ephesus), Turkey
    • Katakolon (Olympia), Greece
    Sailing Dates:
    • May 2026
    • June 2026
    • July 2026
    • August 2026
    • September 2026
    • October 2026
    • November 2026
    interior from
    $1,119
    $160pernight
    oceanview from
    $1,569
    $224pernight
    balcony from
    $1,479
    $211pernight
    suite from
    $1,919
    $274pernight
    Rewards & Bonus Offers:
    • AAdvantage® Members: Earn 2X Miles on Select Sailings
    • Exclusive: Free Onboard Savings Booklet - up to a $1,800 value!
    • AAdvantage® Credit Cardmembers get even more miles
    • Exclusive: Earn up to 20,000 bonus miles!
    • Spring Sale: Up to 50% Off, Free Upgrades & More
    • Drinks, Tips & Wi-Fi Included with Select Fares
    • Call for rates too low to show!
     
    Interior from $1,119
    ($160pernight)
    4.4 rating out of 5  (320 reviews)
  • Sun Princess
    4.1 rating out of 5  (75 reviews)

    7 Night Mediterranean with Greek Isles & Turkey

    Sun Princess

    Departing from: Civitavecchia (Rome), Italy
    Ports of Call:
    • Naples (Pompeii), Italy
    • Souda (Chania), Crete
    • Istanbul, Turkey
    • Mykonos, Greece
    • Piraeus (Athens), Greece
    Sailing Dates:
    • May 2025
    • August 2025
    • September 2025
    interior from
    $1,283
    $183pernight
    oceanview from
    $1,533
    $219pernight
    balcony from
    $2,122
    $303pernight
    suite from
    $2,209
    $316pernight
    Rewards & Bonus Offers:
    • AAdvantage® Members: Earn 2X Miles on Select Sailings
    • Exclusive: Free Onboard Savings Booklet - up to a $1,800 value!
    • AAdvantage® Credit Cardmembers get even more miles
    • Drop & Go Sale: Limited Time Reduced Rates!
    • Spring Sale: Up to 50% Off, Free Upgrades & More
    • Drinks, Tips & Wi-Fi Included with Select Fares
    • Call for rates too low to show!
     
    Interior from $1,283
    ($183pernight)
    4.1 rating out of 5  (75 reviews)
  • Majestic Princess
    4.4 rating out of 5  (440 reviews)

    10 Night Mediterranean

    Majestic Princess

    Departing from: Piraeus (Athens), Greece
    Ports of Call:
    • Mykonos, Greece
    • Rhodes, Greece
    • Kusadasi (Ephesus), Turkey
    • Chania, Crete
    • Katakolon (Olympia), Greece
    • Corfu (Kerkyra), Greece
    • Naples (Pompeii), Italy
    • Civitavecchia (Rome), Italy
    Sailing Dates:
    • May 2025
    interior from
    $813
    $81pernight
    oceanview from
    Not Available
    balcony from
    $1,631
    $163pernight
    suite from
    $2,532
    $253pernight
    Rewards & Bonus Offers:
    • AAdvantage® Members: Earn 2X Miles on Select Sailings
    • Exclusive: Free Onboard Savings Booklet - up to a $1,800 value!
    • AAdvantage® Credit Cardmembers get even more miles
    • Drop & Go Sale: Limited Time Reduced Rates!
    • Drinks, Tips & Wi-Fi Included with Select Fares
    • Spring Sale: Up to 50% Off, Free Upgrades & More
    • Call for rates too low to show!
     
    Interior from $813
    ($81pernight)
    4.4 rating out of 5  (440 reviews)
  • Oosterdam
    4.1 rating out of 5  (893 reviews)

    10 Night Adriatic Allure With History Channel

    Oosterdam

    Departing from: Piraeus (Athens), Greece
    Ports of Call:
    • Souda (Chania), Crete
    • Mykonos, Greece
    • Cruise Dardanelles
    • Istanbul, Turkey
    • Cruise Dardanelles
    • Katakolon (Olympia), Greece
    • Corfu (Kerkyra), Greece
    • Korcula Island, Croatia
    • Trieste (Venice), Italy
    Sailing Dates:
    • August 2025
    interior from
    $1,074
    $107pernight
    oceanview from
    $1,109
    $111pernight
    balcony from
    $1,329
    $133pernight
    suite from
    $1,979
    $198pernight
    Rewards & Bonus Offers:
    • AAdvantage® Members: Earn 2X Miles on Select Sailings
    • Up to 30% Savings + Up to $300 to Spend on Board
    • AAdvantage® Credit Cardmembers get even more miles
    • Free Drinks, Dining, and Excursions with Select Fares
    • Free or Reduced Fares for Guests 3 & 4!
    • No Interest or Approval: Book with No Cruise Payment Due Today
     
    Interior from $1,074
    ($107pernight)
    4.1 rating out of 5  (893 reviews)
  • Norwegian Epic
    3.7 rating out of 5  (3,127 reviews)

    10 Night Greek Isles: Santorini Athens & Florence

    Norwegian Epic - OPEN BAR!

    Departing from: Civitavecchia (Rome), Italy
    Ports of Call:
    • Santorini (Thira), Greece
    • Piraeus (Athens), Greece
    • Argostoli, Kefalonia, Greece
    • Valletta, Malta
    • Messina, Sicily, Italy
    • Naples (Pompeii), Italy
    • Livorno (Florence & Pisa), Italy
    • Cannes, France
    Sailing Dates:
    • October 2025
    interior from
    $1,872
    $187pernight
    oceanview from
    $2,442
    $244pernight
    balcony from
    $2,462
    $246pernight
    suite from
    $2,722
    $272pernight
    Rewards & Bonus Offers:
    • AAdvantage® Members: Earn 2X Miles on Select Sailings
    • Exclusive: Up to $300 to Spend on Board- Call
    • Limited-Time: Up to 25,000 AAdvantage® Bonus Miles
    • Save up to $250 Instantly! Call and Mention: CruiseFirst
    • AAdvantage® Credit Cardmembers get even more miles
    • Kids Sail Free!
     
    Interior from $1,872
    ($187pernight)
    3.7 rating out of 5  (3,127 reviews)
  • Celebrity Ascent
    4.6 rating out of 5  (95 reviews)

    7 Night Italy Spain & French Riviera

    Celebrity Ascent

    Departing from: Barcelona, Spain
    Ports of Call:
    • Nice, France
    • La Spezia (Florence & Pisa), Italy
    • Civitavecchia (Rome), Italy
    • Portofino, Italy
    • Palma De Mallorca, Balearic Islands
    Sailing Dates:
    • June 2025
    • August 2025
    interior from
    $1,565
    $224pernight
    oceanview from
    $1,729
    $247pernight
    balcony from
    $1,717
    $245pernight
    suite from
    $14,787
    $2,112pernight
    Rewards & Bonus Offers:
    • AAdvantage® Members: Earn 2X Miles on Select Sailings
    • CALL: up to a $75 FREE Dining Credit!
    • AAdvantage® Credit Cardmembers get even more miles
    • All-Included: Drinks & Wi-Fi
    • Spring Sale: 75% Off 2nd Guest + Up to $300 in Savings!
     
    Was $7,387 – Save up to 79%
    Interior from $1,565
    ($224pernight)
    4.6 rating out of 5  (95 reviews)
  • Norwegian Viva
    4.3 rating out of 5  (121 reviews)

    10 Night Greek Isles: Santorini Rhodes & Istanbul

    Norwegian Viva

    Departing from: Piraeus (Athens), Greece
    Ports of Call:
    • Mykonos, Greece
    • Kusadasi (Ephesus), Turkey
    • Istanbul, Turkey
    • Volos, Greece
    • Santorini (Thira), Greece
    • Rhodes, Greece
    • Iraklion (Heraklion), Crete
    Sailing Dates:
    • June 2025
    interior from
    $1,404
    $140pernight
    oceanview from
    $1,664
    $166pernight
    balcony from
    $1,884
    $188pernight
    suite from
    $2,734
    $273pernight
    Rewards & Bonus Offers:
    • AAdvantage® Members: Earn 2X Miles on Select Sailings
    • Limited-Time: Up to 25,000 AAdvantage® Bonus Miles
    • AAdvantage® Credit Cardmembers get even more miles
    • 50% Off All Cruises + Enhanced More at Sea Perks
     
    Interior from $1,404
    ($140pernight)
    4.3 rating out of 5  (121 reviews)
  • Legend of the Seas

    7 Night Western Mediterranean

    Legend of the Seas - New Ship!

    Departing from: Civitavecchia (Rome), Italy
    Ports of Call:
    • Naples, Italy
    • Barcelona, Spain
    • Palma De Mallorca, Balearic Islands
    • Marseille (Provence), France
    • La Spezia (Florence & Pisa), Italy
    Sailing Dates:
    • August 2026
    • September 2026
    • October 2026
    interior from
    $1,782
    $255pernight
    oceanview from
    $1,907
    $272pernight
    balcony from
    $1,967
    $281pernight
    suite from
    $3,807
    $544pernight
    Rewards & Bonus Offers:
    • AAdvantage® Members: Earn 2X Miles on Select Sailings
    • AAdvantage® Credit Cardmembers get even more miles
    • 60% Off Second Guest
    • Kids Sail Free!
    • 48-Hour Flash Sale: Up to $700 Instant Savings
    • No Interest or Approval: Book with No Cruise Payment Due Today
     
    Was $3,973 – Save up to 55%
    Interior from $1,782
    ($255pernight)
  • Star Princess

    11 Night Grand Mediterranean

    Star Princess - New Ship!

    Departing from: Barcelona, Spain
    Ports of Call:
    • Marseille (Provence), France
    • Civitavecchia (Rome), Italy
    • Naples (Pompeii), Italy
    • Palermo, Sicily, Italy
    • Cartagena, Spain
    • Gibraltar (U.K.)
    Sailing Dates:
    • October 2025
    interior from
    $1,962
    $178pernight
    oceanview from
    $2,102
    $191pernight
    balcony from
    $2,152
    $196pernight
    suite from
    $2,512
    $228pernight
    Rewards & Bonus Offers:
    • AAdvantage® Members: Earn 2X Miles on Select Sailings
    • Exclusive: Free Onboard Savings Booklet - up to a $1,800 value!
    • AAdvantage® Credit Cardmembers get even more miles
    • Drinks, Tips & Wi-Fi Included with Select Fares
    • Spring Sale: Up to 50% Off, Free Upgrades & More
    • No Interest or Approval: Book with No Cruise Payment Due Today
    • Call for rates too low to show!
     
    Interior from $1,962
    ($178pernight)
  • Celebrity Ascent
    4.6 rating out of 5  (95 reviews)

    10 Night Greece Italy & Croatia

    Celebrity Ascent

    Departing from: Civitavecchia (Rome), Italy
    Ports of Call:
    • Katakolon (Olympia), Greece
    • Corfu (Kerkyra), Greece
    • Dubrovnik, Croatia
    • Split, Croatia
    • Bar, Montenegro
    • Catania, Sicily, Italy
    • Naples, Italy
    Sailing Dates:
    • October 2025
    interior from
    $1,502
    $150pernight
    oceanview from
    $2,102
    $210pernight
    balcony from
    $2,541
    $254pernight
    suite from
    $9,378
    $938pernight
    Rewards & Bonus Offers:
    • AAdvantage® Members: Earn 2X Miles on Select Sailings
    • CALL: up to a $75 FREE Dining Credit!
    • AAdvantage® Credit Cardmembers get even more miles
    • All-Included: Drinks & Wi-Fi
    • Spring Sale: 75% Off 2nd Guest + Up to $300 in Savings!
    • No Interest or Approval: Book with No Cruise Payment Due Today
     
    Was $7,651 – Save up to 80%
    Interior from $1,502
    ($150pernight)
    4.6 rating out of 5  (95 reviews)

Experience the Mediterranean like never before

Explore the region’s rich cultures and legendary landscapes with ease

Step on board and indulge in a seamless travel experience, where you’ll explore historic cities, sun-soaked islands, and breathtaking coastlines — all while enjoying the amenities of a floating five-star hotel.

Sailing the Mediterranean exposes you to a blend of the region’s cultures, history, and stunning scenery in one incredible experience. Explore multiple destinations like Rome, Santorini, Barcelona, and Dubrovnik — without the hassle of packing and unpacking. Get transported to ancient ruins, quaint villages, and vibrant markets. And when you step back aboard your ship, gourmet dining, relaxing spas, and impeccable service is designed for your ultimate comfort.

Experience the perfect balance of adventure and refinement when you set sail on a Mediterranean cruise. And when you book with American Airlines Cruises, you’ll enjoy having all the details taken care of. Our concierges will plan everything from airport transfers to spa reservations, delivering unmatched service and insider knowledge to ensure every detail is flawless. With effortless planning to exclusive perks, we guarantee that your Mediterranean cruise will be unforgettable.

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