Explore the Mediterranean
Sail to multiple iconic destinations and only unpack once
- You May Qualify for One or More Mediterranean Cruises Offers
Mediterranean Cruises
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7 Night Italy & France
Voyager of the Seas
Departing from: Civitavecchia (Rome), ItalyPorts of Call:- Naples, Italy
- Messina, Sicily, Italy
- La Spezia (Florence & Pisa), Italy
- Cannes, France
- Marseille (Provence), France
- Barcelona, Spain
Sailing Dates:- October 2025
interior from$974$139pernightoceanview from$1,072$153pernightbalcony from$1,413$202pernightsuite from$4,450$636pernightInterior from $974($139pernight)4.1 rating out of 5 (1,106 reviews) -
7 Night Western Mediterranean
Allure of the Seas - Revitalized Ship!
Departing from: Barcelona, SpainPorts of Call:- Palma De Mallorca, Balearic Islands
- La Spezia (Florence & Pisa), Italy
- Civitavecchia (Rome), Italy
- Naples, Italy
Sailing Dates:- May 2025
- June 2025
- July 2025
- August 2025
- September 2025
- October 2025
interior from$803$115pernightoceanview from$1,069$153pernightbalcony from$1,273$182pernightsuite from$2,265$324pernightInterior from $803($115pernight)4.4 rating out of 5 (4,027 reviews) -
7 Night Mediterranean with France & Italy
Sun Princess
Departing from: Barcelona, SpainPorts of Call:- Gibraltar (U.K.)
- Marseille (Provence), France
- Genoa, Italy
- La Spezia (Florence & Pisa), Italy
- Civitavecchia (Rome), Italy
Sailing Dates:- May 2025
- August 2025
- April 2026
- May 2026
- June 2026
- July 2026
- August 2026
- September 2026
- October 2026
interior from$840$120pernightoceanview from$1,060$151pernightbalcony from$1,310$187pernightsuite from$1,739$248pernightRewards & Bonus Offers:- AAdvantage® Members: Earn 2X Miles on Select Sailings
- Exclusive: Free Onboard Savings Booklet - up to a $1,800 value!
- AAdvantage® Credit Cardmembers get even more miles
- Exclusive: Earn up to 20,000 bonus miles!
- Drop & Go Sale: Limited Time Reduced Rates!
- Spring Sale: Up to 50% Off, Free Upgrades & More
- Call for rates too low to show!
Interior from $840($120pernight)4.1 rating out of 5 (75 reviews) -
9 Night Italian Riviera & France
Celebrity Equinox
Departing from: Civitavecchia (Rome), ItalyPorts of Call:- Naples, Italy
- La Spezia (Florence & Pisa), Italy
- Portofino, Italy
- Villefranche-Sur-Mer (Nice), France
- Marseille (Provence), France
- Barcelona, Spain
Sailing Dates:- May 2025
- July 2025
- September 2025
- October 2025
interior from$1,057$117pernightoceanview from$1,158$129pernightbalcony from$1,296$144pernightsuite from$3,747$416pernightRewards & Bonus Offers:Was $4,146 – Save up to 75%Interior from $1,057($117pernight)4.3 rating out of 5 (1,963 reviews) -
10 Night Greek Isles: Santorini Athens & Florence
Norwegian Epic - OPEN BAR!
Departing from: Civitavecchia (Rome), ItalyPorts of Call:- Santorini (Thira), Greece
- Piraeus (Athens), Greece
- Katakolon (Olympia), Greece
- Valletta, Malta
- Catania, Sicily, Italy
- Naples (Pompeii), Italy
- Livorno (Florence & Pisa), Italy
- Cannes, France
Sailing Dates:- May 2025
interior from$1,032$103pernightoceanview fromCall for availabilitybalcony from$1,392$139pernightsuite from$1,732$173pernightInterior from $1,032($103pernight)3.7 rating out of 5 (3,127 reviews) -
9 Night Mediterranean: Italy France & Spain
Norwegian Breakaway - OPEN BAR!
Departing from: Barcelona, SpainPorts of Call:- Cannes, France
- Livorno (Florence & Pisa), Italy
- Civitavecchia (Rome), Italy
- Naples (Pompeii), Italy
- Ibiza, Balearic Islands
- Palma De Mallorca, Balearic Islands
Sailing Dates:- May 2025
interior from$950$106pernightoceanview from$1,120$124pernightbalcony from$1,290$143pernightsuite fromCall for availabilityInterior from $950($106pernight)3.8 rating out of 5 (3,532 reviews) -
7 Night Greek Isles
Odyssey of the Seas
Departing from: Civitavecchia (Rome), ItalyPorts of Call:- Santorini (Thira), Greece
- Kusadasi (Ephesus), Turkey
- Mykonos, Greece
- Naples, Italy
Sailing Dates:- May 2025
- June 2025
- July 2025
- August 2025
- September 2025
interior from$1,763$252pernightoceanview from$1,847$264pernightbalcony from$2,123$303pernightsuite from$3,059$437pernightWas $2,756 – Save up to 36%Interior from $1,763($252pernight)4.5 rating out of 5 (490 reviews) -
9 Night Best of Greece
Celebrity Infinity
Departing from: Piraeus (Athens), GreecePorts of Call:- Souda (Chania), Crete
- Santorini (Thira), Greece
- Kusadasi (Ephesus), Turkey
- Mykonos, Greece
- Kavala (Philippi), Greece
- Thessaloniki, Greece
Sailing Dates:- May 2025
- August 2025
- September 2025
- October 2025
interior from$984$109pernightoceanview from$1,154$128pernightbalcony from$1,390$154pernightsuite from$3,017$335pernightWas $4,228 – Save up to 77%Interior from $984($109pernight)4.1 rating out of 5 (1,114 reviews) -
7 Night Mediterranean & Aegean
Enchanted Princess
Departing from: Civitavecchia (Rome), ItalyPorts of Call:- Naples (Pompeii), Italy
- Santorini (Thira), Greece
- Kusadasi (Ephesus), Turkey
- Katakolon (Olympia), Greece
Sailing Dates:- May 2026
- June 2026
- July 2026
- August 2026
- September 2026
- October 2026
- November 2026
interior from$1,119$160pernightoceanview from$1,569$224pernightbalcony from$1,479$211pernightsuite from$1,919$274pernightRewards & Bonus Offers:- AAdvantage® Members: Earn 2X Miles on Select Sailings
- Exclusive: Free Onboard Savings Booklet - up to a $1,800 value!
- AAdvantage® Credit Cardmembers get even more miles
- Exclusive: Earn up to 20,000 bonus miles!
- Spring Sale: Up to 50% Off, Free Upgrades & More
- Drinks, Tips & Wi-Fi Included with Select Fares
- Call for rates too low to show!
Interior from $1,119($160pernight)4.4 rating out of 5 (320 reviews) -
7 Night Mediterranean with Greek Isles & Turkey
Sun Princess
Departing from: Civitavecchia (Rome), ItalyPorts of Call:- Naples (Pompeii), Italy
- Souda (Chania), Crete
- Istanbul, Turkey
- Mykonos, Greece
- Piraeus (Athens), Greece
Sailing Dates:- May 2025
- August 2025
- September 2025
interior from$1,283$183pernightoceanview from$1,533$219pernightbalcony from$2,122$303pernightsuite from$2,209$316pernightRewards & Bonus Offers:- AAdvantage® Members: Earn 2X Miles on Select Sailings
- Exclusive: Free Onboard Savings Booklet - up to a $1,800 value!
- AAdvantage® Credit Cardmembers get even more miles
- Drop & Go Sale: Limited Time Reduced Rates!
- Spring Sale: Up to 50% Off, Free Upgrades & More
- Drinks, Tips & Wi-Fi Included with Select Fares
- Call for rates too low to show!
Interior from $1,283($183pernight)4.1 rating out of 5 (75 reviews) -
10 Night Mediterranean
Majestic Princess
Departing from: Piraeus (Athens), GreecePorts of Call:- Mykonos, Greece
- Rhodes, Greece
- Kusadasi (Ephesus), Turkey
- Chania, Crete
- Katakolon (Olympia), Greece
- Corfu (Kerkyra), Greece
- Naples (Pompeii), Italy
- Civitavecchia (Rome), Italy
Sailing Dates:- May 2025
interior from$813$81pernightoceanview fromNot Availablebalcony from$1,631$163pernightsuite from$2,532$253pernightRewards & Bonus Offers:- AAdvantage® Members: Earn 2X Miles on Select Sailings
- Exclusive: Free Onboard Savings Booklet - up to a $1,800 value!
- AAdvantage® Credit Cardmembers get even more miles
- Drop & Go Sale: Limited Time Reduced Rates!
- Drinks, Tips & Wi-Fi Included with Select Fares
- Spring Sale: Up to 50% Off, Free Upgrades & More
- Call for rates too low to show!
Interior from $813($81pernight)4.4 rating out of 5 (440 reviews) -
10 Night Adriatic Allure With History Channel
Oosterdam
Departing from: Piraeus (Athens), GreecePorts of Call:- Souda (Chania), Crete
- Mykonos, Greece
- Cruise Dardanelles
- Istanbul, Turkey
- Cruise Dardanelles
- Katakolon (Olympia), Greece
- Corfu (Kerkyra), Greece
- Korcula Island, Croatia
- Trieste (Venice), Italy
Sailing Dates:- August 2025
interior from$1,074$107pernightoceanview from$1,109$111pernightbalcony from$1,329$133pernightsuite from$1,979$198pernightRewards & Bonus Offers:- AAdvantage® Members: Earn 2X Miles on Select Sailings
- Up to 30% Savings + Up to $300 to Spend on Board
- AAdvantage® Credit Cardmembers get even more miles
- Free Drinks, Dining, and Excursions with Select Fares
- Free or Reduced Fares for Guests 3 & 4!
- No Interest or Approval: Book with No Cruise Payment Due Today
Interior from $1,074($107pernight)4.1 rating out of 5 (893 reviews) -
10 Night Greek Isles: Santorini Athens & Florence
Norwegian Epic - OPEN BAR!
Departing from: Civitavecchia (Rome), ItalyPorts of Call:- Santorini (Thira), Greece
- Piraeus (Athens), Greece
- Argostoli, Kefalonia, Greece
- Valletta, Malta
- Messina, Sicily, Italy
- Naples (Pompeii), Italy
- Livorno (Florence & Pisa), Italy
- Cannes, France
Sailing Dates:- October 2025
interior from$1,872$187pernightoceanview from$2,442$244pernightbalcony from$2,462$246pernightsuite from$2,722$272pernightInterior from $1,872($187pernight)3.7 rating out of 5 (3,127 reviews) -
7 Night Italy Spain & French Riviera
Celebrity Ascent
Departing from: Barcelona, SpainPorts of Call:- Nice, France
- La Spezia (Florence & Pisa), Italy
- Civitavecchia (Rome), Italy
- Portofino, Italy
- Palma De Mallorca, Balearic Islands
Sailing Dates:- June 2025
- August 2025
interior from$1,565$224pernightoceanview from$1,729$247pernightbalcony from$1,717$245pernightsuite from$14,787$2,112pernightWas $7,387 – Save up to 79%Interior from $1,565($224pernight)4.6 rating out of 5 (95 reviews) -
10 Night Greek Isles: Santorini Rhodes & Istanbul
Norwegian Viva
Departing from: Piraeus (Athens), GreecePorts of Call:- Mykonos, Greece
- Kusadasi (Ephesus), Turkey
- Istanbul, Turkey
- Volos, Greece
- Santorini (Thira), Greece
- Rhodes, Greece
- Iraklion (Heraklion), Crete
Sailing Dates:- June 2025
interior from$1,404$140pernightoceanview from$1,664$166pernightbalcony from$1,884$188pernightsuite from$2,734$273pernightInterior from $1,404($140pernight)4.3 rating out of 5 (121 reviews) -
7 Night Western Mediterranean
Legend of the Seas - New Ship!
Departing from: Civitavecchia (Rome), ItalyPorts of Call:- Naples, Italy
- Barcelona, Spain
- Palma De Mallorca, Balearic Islands
- Marseille (Provence), France
- La Spezia (Florence & Pisa), Italy
Sailing Dates:- August 2026
- September 2026
- October 2026
interior from$1,782$255pernightoceanview from$1,907$272pernightbalcony from$1,967$281pernightsuite from$3,807$544pernightWas $3,973 – Save up to 55%Interior from $1,782($255pernight) -
11 Night Grand Mediterranean
Star Princess - New Ship!
Departing from: Barcelona, SpainPorts of Call:- Marseille (Provence), France
- Civitavecchia (Rome), Italy
- Naples (Pompeii), Italy
- Palermo, Sicily, Italy
- Cartagena, Spain
- Gibraltar (U.K.)
Sailing Dates:- October 2025
interior from$1,962$178pernightoceanview from$2,102$191pernightbalcony from$2,152$196pernightsuite from$2,512$228pernightRewards & Bonus Offers:- AAdvantage® Members: Earn 2X Miles on Select Sailings
- Exclusive: Free Onboard Savings Booklet - up to a $1,800 value!
- AAdvantage® Credit Cardmembers get even more miles
- Drinks, Tips & Wi-Fi Included with Select Fares
- Spring Sale: Up to 50% Off, Free Upgrades & More
- No Interest or Approval: Book with No Cruise Payment Due Today
- Call for rates too low to show!
Interior from $1,962($178pernight) -
10 Night Greece Italy & Croatia
Celebrity Ascent
Departing from: Civitavecchia (Rome), ItalyPorts of Call:- Katakolon (Olympia), Greece
- Corfu (Kerkyra), Greece
- Dubrovnik, Croatia
- Split, Croatia
- Bar, Montenegro
- Catania, Sicily, Italy
- Naples, Italy
Sailing Dates:- October 2025
interior from$1,502$150pernightoceanview from$2,102$210pernightbalcony from$2,541$254pernightsuite from$9,378$938pernightRewards & Bonus Offers:Was $7,651 – Save up to 80%Interior from $1,502($150pernight)4.6 rating out of 5 (95 reviews)
Experience the Mediterranean like never before
Explore the region’s rich cultures and legendary landscapes with ease
Sailing the Mediterranean exposes you to a blend of the region’s cultures, history, and stunning scenery in one incredible experience. Explore multiple destinations like Rome, Santorini, Barcelona, and Dubrovnik — without the hassle of packing and unpacking. Get transported to ancient ruins, quaint villages, and vibrant markets. And when you step back aboard your ship, gourmet dining, relaxing spas, and impeccable service is designed for your ultimate comfort.
Experience the perfect balance of adventure and refinement when you set sail on a Mediterranean cruise. And when you book with American Airlines Cruises, you’ll enjoy having all the details taken care of. Our concierges will plan everything from airport transfers to spa reservations, delivering unmatched service and insider knowledge to ensure every detail is flawless. With effortless planning to exclusive perks, we guarantee that your Mediterranean cruise will be unforgettable.
Search Mediterranean Cruises
- Azamara Cruises from $1,429
- Carnival Cruise Line from $889
- Celebrity Cruises from $750
- Costa Cruises from $357
- Cunard from $849
- Disney Cruise Line from $1,696
- Holland America Line from $899
- MSC Cruises from $246
- Norwegian Cruise Line from $764
- Oceania Cruises from $2,099
- Ponant from $3,070
- Princess Cruises from $607
- Regent Seven Seas Cruises from $4,799
- Royal Caribbean from $528
- Seabourn from $4,199
- SeaDream Yacht Club from $4,999
- Silversea Cruises from $3,450
- The Ritz-Carlton Yacht Collection from $6,300
- Viking Ocean Cruises from $2,799
- Windstar Cruises from $2,126
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