Panama Canal Cruises

Sail Central America from Atlantic to Pacific

View natural beauty and an engineering marvel across the Panama Canal

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Recommended Panama Canal Cruises

Featured Panama Canal Cruises

Experience the trip of a lifetime as you navigate the 50-mile Panama Canal onboard a cheap Panama Canal cruise, including one of these highly-rated Panama Canal cruises:
  • Carnival Legend
    3.9 rating out of 5  (2,210 reviews)

    10 Night Panama Canal

    Carnival Legend

    Departing from: Galveston, Texas
    Ports of Call:
    • Cozumel, Mexico
    • Puerto Limon, Costa Rica
    • Colon, Panama
    • Mahogany Bay (Roatan), Bay Islands, Honduras
    Sailing Dates:
    • October 2025
    • December 2025
    • March 2026
    interior from
    $984
    $98pernight
    oceanview from
    $1,324
    $132pernight
    balcony from
    $1,669
    $167pernight
    suite from
    $3,515
    $352pernight
    Rewards & Bonus Offers:
    • AAdvantage® Members: Earn 2X Miles on Select Sailings
    • VIFP Members: Unlock big savings!
    • AAdvantage® Credit Cardmembers get even more miles
    • No Interest or Approval: Book with No Cruise Payment Due Today
    • Up to 2-Category Upgrade!
     
    Interior from $984
    ($98pernight)
    3.9 rating out of 5  (2,210 reviews)
  • Carnival Legend
    3.9 rating out of 5  (2,210 reviews)

    8 Night Panama Canal

    Carnival Legend

    Departing from: Tampa, Florida
    Ports of Call:
    • Puerto Limon, Costa Rica
    • Colon, Panama
    • George Town, Grand Cayman
    Sailing Dates:
    • January 2027
    • March 2027
    interior from
    $1,039
    $130pernight
    oceanview from
    $1,189
    $149pernight
    balcony from
    $1,389
    $174pernight
    suite from
    $2,231
    $279pernight
    Rewards & Bonus Offers:
    • VIFP Members: Unlock big savings!
     
    Interior from $1,039
    ($130pernight)
    3.9 rating out of 5  (2,210 reviews)
  • Carnival Spirit
    4 rating out of 5  (998 reviews)

    16 Night Panama Canal Carnival Journeys - Eastbound

    Carnival Spirit

    Departing from: Seattle, Washington
    Ports of Call:
    • Cabo San Lucas, Mexico
    • Puntarenas, Costa Rica
    • Panama Canal Full Transit
    • Cartagena, Colombia
    • New Orleans, Louisiana
    Sailing Dates:
    • October 2025
    interior from
    $993
    $62pernight
    oceanview from
    $1,333
    $83pernight
    balcony from
    $1,628
    $102pernight
    suite from
    Call for availability
    Rewards & Bonus Offers:
    • AAdvantage® Members: Earn 2X Miles on Select Sailings
    • VIFP Members: Unlock big savings!
    • AAdvantage® Credit Cardmembers get even more miles
    • No Interest or Approval: Book with No Cruise Payment Due Today
     
    Interior from $993
    ($62pernight)
    4 rating out of 5  (998 reviews)
  • Rotterdam
    4.4 rating out of 5  (290 reviews)

    12 Night Panama Canal Discovery: Costa Rica & Greater Antilles

    Rotterdam

    Departing from: Ft. Lauderdale (Port Everglades), Florida
    Ports of Call:
    • Relaxaway, Half Moon Cay, Bahamas (Cruiseline Private Island)
    • Willemstad, Curacao
    • Cartagena, Colombia
    • Panama Canal (Partial Transit)
    • Colon, Panama
    • Puerto Limon, Costa Rica
    • George Town, Grand Cayman
    Sailing Dates:
    • October 2025
    • December 2025
    • February 2026
    • March 2026
    interior from
    $1,199
    $100pernight
    oceanview from
    $1,699
    $142pernight
    balcony from
    $1,899
    $158pernight
    suite from
    $2,899
    $242pernight
    Rewards & Bonus Offers:
    • AAdvantage® Members: Earn 2X Miles on Select Sailings
    • Up to 30% Savings + Up to $300 to Spend on Board
    • Exclusive: Free Tamarind Dinner for 2 - Call
    • AAdvantage® Credit Cardmembers get even more miles
    • Free Drinks, Dining, and Excursions with Select Fares
    • Free or Reduced Fares for Guests 3 & 4!
    • Call for rates too low to show!
     
    Interior from $1,199
    ($100pernight)
    4.4 rating out of 5  (290 reviews)
  • Celebrity Summit
    4.1 rating out of 5  (2,265 reviews)

    16 Night Panama Canal - Eastbound

    Celebrity Summit

    Departing from: San Pedro (Los Angeles), California
    Ports of Call:
    • Puerto Vallarta, Mexico
    • Puerto Quetzal, Guatemala
    • Puntarenas, Costa Rica
    • Panama Canal Full Transit
    • Cartagena, Colombia
    • Falmouth, Jamaica
    • George Town, Grand Cayman
    • Ft. Lauderdale (Port Everglades), Florida
    Sailing Dates:
    • September 2025
    interior from
    Call for availability
    oceanview from
    $1,617
    $101pernight
    balcony from
    $2,867
    $179pernight
    suite from
    $17,377
    $1,086pernight
    Rewards & Bonus Offers:
    • AAdvantage® Members: Earn 2X Miles on Select Sailings
    • AAdvantage® Credit Cardmembers get even more miles
    • All-Included: Drinks & Wi-Fi
    • Spring Sale: 75% Off 2nd Guest + Up to $300 in Savings!
    • No Interest or Approval: Book with No Cruise Payment Due Today
     
    Was $6,291 – Save up to 74%
    Oceanview from $1,617
    ($101pernight)
    4.1 rating out of 5  (2,265 reviews)
  • Norwegian Jewel
    3.7 rating out of 5  (2,431 reviews)

    11 Night Panama Canal Partial Transit: Mexico Costa Rica & Belize

    Norwegian Jewel - OPEN BAR!

    Departing from: Miami, Florida
    Ports of Call:
    • George Town, Grand Cayman
    • Cartagena, Colombia
    • Panama Canal (Partial Transit)
    • Colon, Panama
    • Puerto Limon, Costa Rica
    • Harvest Caye, Belize
    • Cozumel, Mexico
    Sailing Dates:
    • December 2025
    • January 2026
    • March 2026
    interior from
    $1,330
    $121pernight
    oceanview from
    $1,520
    $138pernight
    balcony from
    $2,380
    $216pernight
    suite from
    $2,679
    $244pernight
    Rewards & Bonus Offers:
    • AAdvantage® Members: Earn 2X Miles on Select Sailings
    • Limited-Time: Up to 25,000 AAdvantage® Bonus Miles
    • Save up to $250 Instantly! Call and Mention: CruiseFirst
    • AAdvantage® Credit Cardmembers get even more miles
    • Reduced Fares for Third & Fourth Guests
    • 50% Off All Cruises + Enhanced More at Sea Perks
     
    Interior from $1,330
    ($121pernight)
    3.7 rating out of 5  (2,431 reviews)
  • Caribbean Princess
    3.9 rating out of 5  (1,921 reviews)

    12 Night Panama Canal with Costa Rica & Caribbean

    Caribbean Princess

    Departing from: Ft. Lauderdale (Port Everglades), Florida
    Ports of Call:
    • George Town, Grand Cayman
    • Falmouth, Jamaica
    • Puerto Limon, Costa Rica
    • Panama Canal (Partial Transit)
    • Colon, Panama
    • Oranjestad, Aruba
    • Willemstad, Curacao
    Sailing Dates:
    • November 2025
    interior from
    $1,238
    $103pernight
    oceanview from
    $1,318
    $110pernight
    balcony from
    $1,948
    $162pernight
    suite from
    $2,398
    $200pernight
    Rewards & Bonus Offers:
    • AAdvantage® Members: Earn 2X Miles on Select Sailings
    • Exclusive: Free Onboard Savings Booklet - up to a $1,800 value!
    • Exclusive: Up to $100 to Spend on Board - Call
    • AAdvantage® Credit Cardmembers get even more miles
    • Spring Sale: Up to 50% Off, Free Upgrades & More
    • Drinks, Tips & Wi-Fi Included with Select Fares
    • Call for rates too low to show!
     
    Interior from $1,238
    ($103pernight)
    3.9 rating out of 5  (1,921 reviews)
  • Caribbean Princess
    3.9 rating out of 5  (1,921 reviews)

    16 Night Panama Canal - Ocean to Ocean

    Caribbean Princess

    Departing from: San Pedro (Los Angeles), California
    Ports of Call:
    • Puerto Vallarta, Mexico
    • Huatulco, Mexico
    • Puerto Chiapas (Tapachula), Mexico
    • Puntarenas, Costa Rica
    • Panama City (Fuerte Amador), Panama
    • Panama Canal Full Transit
    • Oranjestad, Aruba
    • Ft. Lauderdale (Port Everglades), Florida
    Sailing Dates:
    • September 2025
    interior from
    $1,298
    $81pernight
    oceanview from
    $1,378
    $86pernight
    balcony from
    $2,078
    $130pernight
    suite from
    $2,818
    $176pernight
    Rewards & Bonus Offers:
    • AAdvantage® Members: Earn 2X Miles on Select Sailings
    • Exclusive: Free Onboard Savings Booklet - up to a $1,800 value!
    • AAdvantage® Credit Cardmembers get even more miles
    • Exclusive: Earn up to 20,000 bonus miles!
    • Spring Sale: Up to 50% Off, Free Upgrades & More
    • Drinks, Tips & Wi-Fi Included with Select Fares
    • Call for rates too low to show!
     
    Interior from $1,298
    ($81pernight)
    3.9 rating out of 5  (1,921 reviews)
  • Serenade of the Seas
    4.1 rating out of 5  (1,829 reviews)

    13 Night Panama Canal Eastward

    Serenade of the Seas

    Departing from: San Diego, California
    Ports of Call:
    • Puerto Vallarta, Mexico
    • Huatulco, Mexico
    • Puntarenas, Costa Rica
    • Panama Canal Full Transit
    • Cartagena, Colombia
    • Miami, Florida
    Sailing Dates:
    • September 2025
    interior from
    $1,508
    $116pernight
    oceanview from
    $1,928
    $148pernight
    balcony from
    $5,910
    $455pernight
    suite from
    Call for availability
    Rewards & Bonus Offers:
    • AAdvantage® Members: Earn 2X Miles on Select Sailings
    • Exclusive Bonus: up to $100 to Spend Onboard
    • AAdvantage® Credit Cardmembers get even more miles
    • 60% Off Second Guest
    • Kids Sail Free!
    • 48-Hour Flash Sale: Up to $700 Instant Savings
     
    Was $3,028 – Save up to 50%
    Interior from $1,508
    ($116pernight)
    4.1 rating out of 5  (1,829 reviews)
  • Norwegian Joy
    4.2 rating out of 5  (998 reviews)

    15 Night Panama Canal: Mexico Costa Rica & Colombia

    Norwegian Joy - OPEN BAR!

    Departing from: San Pedro (Los Angeles), California
    Ports of Call:
    • Cabo San Lucas, Mexico
    • Acapulco, Mexico
    • Puerto Quetzal, Guatemala
    • Puerto Caldera (Puntarenas), Costa Rica
    • Panama City, Panama
    • Panama Canal Full Transit
    • Cartagena, Colombia
    • Miami, Florida
    Sailing Dates:
    • October 2025
    interior from
    $1,671
    $111pernight
    oceanview from
    $2,101
    $140pernight
    balcony from
    $2,871
    $191pernight
    suite from
    $2,951
    $197pernight
    Rewards & Bonus Offers:
    • AAdvantage® Members: Earn 2X Miles on Select Sailings
    • Limited-Time: Up to 25,000 AAdvantage® Bonus Miles
    • Save up to $250 Instantly! Call and Mention: CruiseFirst
    • AAdvantage® Credit Cardmembers get even more miles
    • 50% Off All Cruises + Enhanced More at Sea Perks
    • No Interest or Approval: Book with No Cruise Payment Due Today
     
    Interior from $1,671
    ($111pernight)
    4.2 rating out of 5  (998 reviews)
  • Norwegian Pearl
    3.8 rating out of 5  (2,075 reviews)

    11 Night Panama Canal: Mexico Costa Rica & Belize

    Norwegian Pearl - OPEN BAR!

    Departing from: Miami, Florida
    Ports of Call:
    • Ocho Rios, Jamaica
    • Cartagena, Colombia
    • Cruise Gatun Lake And Panama Canal
    • Colon, Panama
    • Puerto Limon, Costa Rica
    • Harvest Caye, Belize
    • Cozumel, Mexico
    Sailing Dates:
    • December 2025
    • January 2026
    interior from
    $1,662
    $151pernight
    oceanview from
    $2,012
    $183pernight
    balcony from
    $3,112
    $283pernight
    suite from
    $3,212
    $292pernight
    Rewards & Bonus Offers:
    • AAdvantage® Members: Earn 2X Miles on Select Sailings
    • Exclusive: Up to $200 to Spend on Board- Call
    • Limited-Time: Up to 25,000 AAdvantage® Bonus Miles
    • Save up to $250 Instantly! Call and Mention: CruiseFirst
    • AAdvantage® Credit Cardmembers get even more miles
    • Kids Sail Free!
     
    Interior from $1,662
    ($151pernight)
    3.8 rating out of 5  (2,075 reviews)
  • Rotterdam
    4.4 rating out of 5  (290 reviews)

    12 Night Panama Canal Holiday: Costa Rica & Greater Antilles

    Rotterdam

    Departing from: Ft. Lauderdale (Port Everglades), Florida
    Ports of Call:
    • Relaxaway, Half Moon Cay, Bahamas (Cruiseline Private Island)
    • Willemstad, Curacao
    • Cartagena, Colombia
    • Panama Canal (Partial Transit)
    • Colon, Panama
    • Puerto Limon, Costa Rica
    • Ocho Rios, Jamaica
    Sailing Dates:
    • December 2025
    interior from
    $1,799
    $150pernight
    oceanview from
    $2,299
    $192pernight
    balcony from
    $2,599
    $217pernight
    suite from
    $3,899
    $325pernight
    Rewards & Bonus Offers:
    • AAdvantage® Members: Earn 2X Miles on Select Sailings
    • Up to 30% Savings + Up to $300 to Spend on Board
    • AAdvantage® Credit Cardmembers get even more miles
    • Free Drinks, Dining, and Excursions with Select Fares
    • No Interest or Approval: Book with No Cruise Payment Due Today
    • Call for rates too low to show!
     
    Interior from $1,799
    ($150pernight)
    4.4 rating out of 5  (290 reviews)
  • Caribbean Princess
    3.9 rating out of 5  (1,921 reviews)

    12 Night Panama Canal with Costa Rica & Caribbean Holiday

    Caribbean Princess

    Departing from: Ft. Lauderdale (Port Everglades), Florida
    Ports of Call:
    • Oranjestad, Aruba
    • Willemstad, Curacao
    • Cartagena, Colombia
    • Panama Canal (Partial Transit)
    • Colon, Panama
    • Puerto Limon, Costa Rica
    • George Town, Grand Cayman
    Sailing Dates:
    • December 2025
    interior from
    $1,798
    $150pernight
    oceanview from
    $2,038
    $170pernight
    balcony from
    $3,098
    $258pernight
    suite from
    $3,818
    $318pernight
    Rewards & Bonus Offers:
    • AAdvantage® Members: Earn 2X Miles on Select Sailings
    • Exclusive: Free Onboard Savings Booklet - up to a $1,800 value!
    • Exclusive: Up to $100 to Spend on Board - Call
    • AAdvantage® Credit Cardmembers get even more miles
    • Spring Sale: Up to 50% Off, Free Upgrades & More
    • Drinks, Tips & Wi-Fi Included with Select Fares
    • Call for rates too low to show!
     
    Interior from $1,798
    ($150pernight)
    3.9 rating out of 5  (1,921 reviews)
  • Celebrity Ascent
    4.6 rating out of 5  (98 reviews)

    11 Night Panama Canal & Southern Caribbean

    Celebrity Ascent

    Departing from: Ft. Lauderdale (Port Everglades), Florida
    Ports of Call:
    • Cartagena, Colombia
    • Panama Canal (Partial Transit)
    • Colon, Panama
    • Oranjestad, Aruba
    • Willemstad, Curacao
    • Kralendijk, Bonaire
    Sailing Dates:
    • March 2026
    interior from
    $2,587
    $235pernight
    oceanview from
    $2,970
    $270pernight
    balcony from
    $3,604
    $328pernight
    suite from
    Call for availability
    Rewards & Bonus Offers:
    • AAdvantage® Members: Earn 2X Miles on Select Sailings
    • AAdvantage® Credit Cardmembers get even more miles
    • All-Included: Drinks & Wi-Fi
    • Spring Sale: 75% Off 2nd Guest + Up to $300 in Savings!
    • No Interest or Approval: Book with No Cruise Payment Due Today
     
    Was $6,404 – Save up to 60%
    Interior from $2,587
    ($235pernight)
    4.6 rating out of 5  (98 reviews)

Panama Canal Cruises ... Unbeatable Vacations For Less

Enjoy Huge Savings & Offers on Panama Canal Cruises

Take a break from ordinary vacations, and choose the adventure of a lifetime with a Panama Canal cruise. Offering fantastic voyages through both old and new ports with great shopping, culture and plenty of ways to wine and dine, there's never been a better way to escape the everyday. Most Panama Canal cruise vacations average around 14 nights, giving you and the rest of your party all the time in the world to soak up the sights and get away from it all.

Perhaps your Panama Canal cruise vacation will take you through the port of Huatulco, Mexico, where quaint villages meet upscale resorts - plus plenty of white-sand beaches to enjoy the waters of paradise. Enjoy a livelier environment in Cabo San Lucas, and dine at the world-renown Cabo Wabo Cantina Concert Hall & Restaurant, owned by rocker, Sammy Hagar. If you'd prefer to spend your time enjoying all the water sports that a Panama Canal cruise has to offer, don't miss the unbeatable scuba diving and snorkeling opportunities in Puntarenas, Costa Rica.

Regardless of which fantastic Panama Canal cruise itinerary you choose, you're sure to experience luxurious accommodations, fine dining options and daily entertainment aboard your cruise ship. Why settle for the hassle of multiple hotel stays and inconvenient transportation when you can have it all with a cruise vacation? Simply book your Panama Canal cruise getaway through American Airlines Cruises, and take advantage of the best prices and deals around.

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